Manufactured by:TriBio Science
RUO

Salinomycin Na, Cancer stem cell inhibitor

A polyether ionophore with antibiotic and anti-cancer properties. It induces cell death in some types of cancer cells such as breast, lung, gastric cancer, leukemia and osteosarcoma. Displays selective toxicity for cancer stem cells. Induces rapid mitochondrial hyperpolarization. Induces...

SKU:
ABM148699-1
Manufacturer SKU
TBI2654-10MG | TBI2654-50MG
Product type
Biochemical Inhibitors
TargetCancer stem cell
Purity>97%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

A polyether ionophore with antibiotic and anti-cancer properties. It induces cell death in some types of cancer cells such as breast, lung, gastric cancer, leukemia and osteosarcoma. Displays selective toxicity for cancer stem cells. Induces rapid mitochondrial hyperpolarization. Induces selective cytotoxicity to MCF-7 mammosphere cells via the hedgehog signaling pathway. Reduces doxorubicin resistance of breast tumor cells by inhibiting drug efflux pump expression and activity. Kills cancer stem cells by sequestering iron

Key facts & specifications
Also known as
From Streptomyces albus
Molecular weight
773
Form / buffer
Powder
Activity
A polyether ionophore with antibiotic and anti-cancer properties. It induces cell death in some types of cancer cells such as breast, lung, gastric cancer, leukemia and osteosarcoma. Displays selective toxicity for cancer stem cells. Induces rapid mitochondrial hyperpolarization. Induces selective cytotoxicity to MCF-7 mammosphere cells via the hedgehog signaling pathway. Reduces doxorubicin resistance of breast tumor cells by inhibiting drug efflux pump expression and activity. Kills cancer stem cells by sequestering iron.
Molecular formula
C 42 H 69 O 11 Na
Solubility
Soluble in DMSO (up to 40 mg/ml)
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI2654-10MG | TBI2654-50MG
CAS number
55721-31-8
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£49.00