Manufactured by:TriBio Science
RUO

Sulindac sulfone, Modulates beta-catenin-mediated effects

Metabolite of the cyclooxygenase inhibitor sulindac that induces apoptosis via inhibition of type 5 phosphodiesterases. Sulindac sulfone does not inhibit cyclooxygenase at physiological concentrations but does inhibit K-ras-dependent cyclooxygenase-2 expression in colon cancer cells

SKU:
ABM148802-1
Manufacturer SKU
TBI1122-25MG | TBI1122-5MG
Product type
Biochemical Inhibitors
TargetModulates beta-catenin-mediated effects
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Metabolite of the cyclooxygenase inhibitor sulindac that induces apoptosis via inhibition of type 5 phosphodiesterases. Sulindac sulfone does not inhibit cyclooxygenase at physiological concentrations but does inhibit K-ras-dependent cyclooxygenase-2 expression in colon cancer cells

Key facts & specifications
Also known as
(Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid
Molecular weight
372.41
Form / buffer
powder
Activity
Metabolite of the cyclooxygenase inhibitor sulindac that induces apoptosis via inhibition of type 5 phosphodiesterases. Sulindac sulfone does not inhibit cyclooxygenase at physiological concentrations but does inhibit K-ras-dependent cyclooxygenase-2 expression in colon cancer cells.
Molecular formula
C 20 H 17 FO 4 S
Solubility
Soluble in DMSO (up to 25 mg/ml).
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI1122-25MG | TBI1122-5MG
CAS number
59864-04-9
Storage, stability & shipping
Storage conditions
RT
Shipped at
4°C
Long-term storage
RT
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£294.00