Tiagabine is a clinically useful anticonvulsant. It is also used to treat anxiety/panic disorder and neuropathic pain. Inhibits GABA-reuptake (IC50 [3H]GABA uptake = 67 nM) via inhibiting GABA transporter 1(GAT1) blocking both neuronal and glial GABA re-uptake
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Tiagabine is a clinically useful anticonvulsant. It is also used to treat anxiety/panic disorder and neuropathic pain. Inhibits GABA-reuptake (IC50 [3H]GABA uptake = 67 nM) via inhibiting GABA transporter 1(GAT1) blocking both neuronal and glial GABA re-uptake
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