Catechol O-methyltransferase inhibitor (COMT), inhibiting both brain and peripheral enzymes. Potent inhibitor of alpha-synuclein and beta-amyloid oligomerization and fibrillogenesis protecting against extracellular toxicity. Binds to transthyretin (TTR) with high affinity (21 to 58 nM) and...
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Catechol O-methyltransferase inhibitor (COMT), inhibiting both brain and peripheral enzymes. Potent inhibitor of alpha-synuclein and beta-amyloid oligomerization and fibrillogenesis protecting against extracellular toxicity. Binds to transthyretin (TTR) with high affinity (21 to 58 nM) and inhibits TTR aggregation in human plasma and prevents TTR-induced cytotoxicity in vitro. Stabilizes TTR in mice and humans in vivo. Inhibits O-methylation of exogenous polyphenols such as EGCG. Cell permeable. Orally bioavailable
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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