Manufactured by:TriBio Science
RUO

UNC0224, G9a histone methyl transferase inhibitor

Ferroptosis suppressor protein (FSP1) inhibitor Potent inhibitor of histone methyltransferases G9a / EHMT2 (IC 50 = 15 nM) and GLP / EHMT1 (IC 50 ~ 39 nM) but not SET7/9 and SET8. Has been employed, as part of a small molecule cocktail, to reprogram somatic cells to pluripotent stem cells

SKU:
ABM148910-1
Manufacturer SKU
TBI5216-1MG | TBI5216-5MG
Product type
Biochemical Inhibitors
TargetG9a histone methyl transferase
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Ferroptosis suppressor protein (FSP1) inhibitor

Potent inhibitor of histone methyltransferases G9a / EHMT2 (IC 50 = 15 nM) and GLP / EHMT1 (IC 50 ~ 39 nM) but not SET7/9 and SET8. Has been employed, as part of a small molecule cocktail, to reprogram somatic cells to pluripotent stem cells

Key facts & specifications
Also known as
7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine
Molecular weight
485.7
Form / buffer
Powder
Activity
Potent inhibitor of histone methyltransferases G9a / EHMT2 (IC 50 = 15 nM) and GLP / EHMT1 (IC 50 ~ 39 nM) but not SET7/9 and SET8. Has been employed, as part of a small molecule cocktail, to reprogram somatic cells to pluripotent stem cells.
Molecular formula
C 26 H 43 N 7 O 2
Solubility
Soluble in DMSO (50 mg/ml)
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI5216-1MG | TBI5216-5MG
CAS number
1197196-48-7
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£87.00